FACULTY: Science
DEPARTMENT: Microbiology and Parasitology
NAME OF STAFF: Roland N. NDIP
E-mail: ndip.roland@ubuea.cm
Secondary E-mail: ndip3@yahoo.com
Tel: + 237- 676558872
GRADE: Professor
BRIEF EDUCATIONAL BACKGROUND
Edo State University, Ekpoma, Nigeria. 1991 – 1994, Ph.D Microbiology (Medical).
University of Lagos, Lagos, Nigeria. 1990 – 1991, M.Sc.(Distinction), Microbiology (Medical).
University of Lagos, Lagos, Nigeria. 1987 – 1990, B.Sc. (Hons, Second Class Upper Division), Microbiology.
RESEARCH INTEREST AREA
Medical Microbiology with a bias in Medical Bacteriology, Molecular Epidemiology and Antimicrobial Chemotherapy.
MASTER DESSERTATIONS SUPERVISED
I have supervised 42 MSc students:
-Helicobacter pylori isolates recovered from patients presenting with gastroduodenal pathologies: antimicrobial susceptibility pattern of isolates.
-Phyto-chemical analysis and bioactivity of Garcinia kola (Heckel) seeds on selected bacterial pathogens.
-Molecular detection and drug susceptibility of Mycobacterium tuberculosis complex in raw milk from a major dairy farm in the Nkonkobe Region, Eastern Cape Province, South Africa.
-Genetic diversity of Pseudomonas aeruginosa recovered from Clinical and Environmental samples in the Buea health district of Cameroon.
PhD THESES SUPERVISED
1.Molecular and phenotypic characterization of Helicobacter pylori isolates from dyspeptic patients in the Eastern Cape Province of South Africa. Current PhD study, University of Fort Hare, South Africa. Year of Defence 2011
2.Molecular Characterization of Clinical Isolates of Mycobacterium tuberculosis from South African patients: Sensitivity of isolates to Plant-derived products. Year of Defence 2011
3.Pharmacogenetic studies in HIV infected South Africans. Pharmacogenetic studies in HIV infected South Africans Year of Defence 2012
4. Phytochemical analysis and bioactivity of selected South African Medicinal plants on clinical isolates of Helicobacter pylori Year of Defence 2012
5.Antibacterial and phytochemical studies of selected South African honeys on clinical isolates of Helicobacter pylori. Year of Defence 2012
6.Antifungal, phytochemical and toxicological analysis of selected medicinal plants used in the treatment of secondary HIV infections in South Africa. Year of Defence 2013
7.Studies on the phytochemical, antioxidant and anticancer property of Peltophorum africanum Year of Defence 2013
8.Studies on the phenotypic and genotypic characterization of foodborne pathogens isolated from various foods sold in roadside cafeterias of Alice, Eastern Cape Province, South Africa. Year of Defence 2013
9.Detection and characterization of Ehrlichia ruminantium from cattle and Amblyomma variegatum ticks in Cameroon Year of Defence 2014
PUBLICATIONS
1. B. I. Okeleye Vuyokazi Nongogo Noxolo T. Mkwetshana R. N. Ndip (2015). Polyphenolic content and in vitro antioxidant evaluation of the stem bark extract of peltophorum africanum sond (fabaceae). African Journal of Traditional Complementary and Alternative Medicine. 12(1):1-8
2. Nicoline F. Tanih, Eunice Sekwadi, Roland N. Ndip, and Pascal O. Bessong (2015).
Detection of Pathogenic Escherichia coli and Staphylococcus aureus from Cattle and Pigs Slaughtered in Abattoirs in Vhembe District, South Africa. The Scientific World Journal Volume 2015, Article ID 195972,.doi.org/10.1155/2015/195972
3. Otang WM, Grierson DS, Ndip RN (2014). Cytotoxicity of three South african medicinal plants using the chang liver cell line. African Journal of Traditional Complementary and Alternative Medicine. 11(2):324-9.
4. Caine LA, Nwodo UU, Okoh AI, Ndip RN, Green E (2014). Occurrence of virulence genes associated with diarrheagenic Escherichia coli isolated from raw cow’s milk from two commercial dairy farms in the Eastern Cape Province, South Africa. International Journal of Environmental Research and Public Health.11(11):11950-63.
5. Bhembe NL, Nwodo UU, Govender S, Hayes C, Ndip RN, Okoh AI, Green E (2014). Molecular detection and characterization of resistant genes in Mycobacterium tuberculosis complex from DNA isolated from tuberculosis patients in the Eastern Cape Province South Africa. BMC Infectious Disease. 14:479.
6. Masebe T, Bessong PO, Ndip RN, Meyer D (2014). Genetic variants of APOC3 promoter and HLA-B genes in an HIV infected cohort in northern South Africa: a pilot study. International Journal of Molecular Science.15(7):11403-15.
7. Mirriam E. Nyenje, Nicoline F. Tanih, Roland N. Ndip (2014). Comparison of M.I.C. Evaluator test with the Broth Microdilution method for Antimicrobial Susceptibility Testing of Enterobacter cloacae Isolated from Cooked Food Samples. Pakistan Journal of Pharmaceutical Science. 27(1):63-6.
8. Benjamin I. Okeleye , Noxolo T. Mkwetshana and Roland N. Ndip (2013). Evaluation of the antibacterial and antifungal potential of Peltophorum africanum: toxicological effect on human liver cell line. Scientific World Journal. 2013; 2013:878735. doi: 10.1155/2013/878735.
9. Nicoline Fri Tanih, Roland Ndip Ndip (2013).The Acetone Extract of Sclerocarya birrea (Anacardiaceae) possess antiproliferative and apoptotic potential against Human Breast Cancer Cell Lines (MCF7). Scientific World Journal. 2013; 2013:956206. doi: 10.1155/2013/956206.
10. Ezekiel Green, Lawrence C. Obi, Anthony I. Okoh, Maphoshane. Nchabeleng, Babsie. E. de Villiers, Tomas Letsoalo, Anwar A. Hoosen, Pascal O. Bessong, Roland N. Ndip (2013). IS6110 restriction fragment length polymorphism typing of drug resistant isolates of Mycobacterium tuberculosis from North East of South Africa. Journal of Health, Population and Nutrition. 31(1):1-10.
11. Seraphine N. Esemu, Willington O. Besong, Roland N. Ndip, Lucy M. Ndip (2013). Prevalence of Ehrlichia ruminantium in adult Amblyomma variegatum collected from cattle in Cameroon. Experimental and Applied Acarology. 59(3):377-87.
12. Adefuye AO, Ndip RN (2013). Phytochemical analysis and bioactivity of the ethyl acetate extract of the stem bark of Bridelia micrantha. Pharmacognosy Magazine. 9(33):45-50
13. Mirriam E. Nyenje and Roland N. Ndip (2013). The challenges of foodborne pathogens and antimicrobial chemotherapy: A global perspective. African Journal of Microbiology Research. 7(14): 1158-1172.
14. Nicoline F. Tanih, Roland N. Ndip (2013). Molecular detection of Antibiotic Resistance in South African Isolates of Helicobacter pylori. Gastroenterology Research and Practice. 2013; 2013:259457. doi: 10.1155/2013/259457
15. Wilfred M. Otang , Donald S. Grierson, and Roland N. Ndip (2013) Assessment of cytotoxicity of three South African medicinal plants using the brine shrimp (Artemia salina) assay. African Journal of Pharmacy and Pharmacology
16. Christy E. Manyi –Loh , Anna M. Clarke, Ezekiel Green, Roland N. Ndip (2013). Inhibitory and bactericidal activity of selected South African honeys and their solvent extracts against clinical isolates of Helicobacter pylori. Pakistan Journal of Pharmaceutical Science. 26(5):897-906
17. Nicoline F. Tanih, Roland N. Ndip (2013). A South African perspective on Helicobacter pylori: Prevalence, Epidemiology and Antimicrobial Chemotherapy. African Journal of Microbiology Research. 7(21): 2430 -2437
18. Mirriam E. Nyenje , Ezekiel Green and Roland N. Ndip (2013). Evaluation of the Effect of Different Growth Media and Temperature on the Suitability of Biofilm Formation by Enterobacter cloacae Strains Isolated from Food Samples in South Africa. Molecules.18: 9582-9593
19. Mirriam E. Nyenje , Collins E. Odjadjare , Nicoline F. Tanih, Ezekiel Green and Roland N. Ndip (2012). Food borne pathogens recovered from ready- to – eat foods from roadside cafeterias and retail outlets in Alice, Eastern Cape province, South Africa: public health implications. International Journal of Environmental Research and Public Health. 9: 2608 – 2619.
20. Mirriam E. Nyenje , Nicoline F. Tanih , Ezekiel Green and Roland N. Ndip (2012) Current status on antibiogram of Listeria ivanovii and Enterobacter cloacae isolated from ready-to-eat foods in Alice, South Africa. International Journal of Environmental Research and Public Health. 9: 3101 – 3114
21. Blessing Silaigwana, Ezekiel Green, Roland Ndip (2012). Molecular detection and drug susceptibility of Mycobacterium tuberculosis complex from raw cattle milk at a dairy farm in the Nkonkobe region of South Africa: A pilot study. International Journal of Environmental Research and Public Health. 9 (6): 2045 – 2056
22. Christy E. Manyi –Loh , Anna M. Clarke, Roland N. Ndip. (2012). Detection of phytoconstituents in column fractions of n- hexane extract of Goldcrest honey exhibiting anti-Helicobacter pylori activity. Archives of Medical Research. 43 (3): 197 – 204
23. Christinah Seanego, Roland N. Ndip (2012). Identification and antibacterial evaluation of bioactive compounds from Garcinia kola (Heckel) seeds. Molecules. 17 (6): 6569 – 6584
24. Nicoline F. TANIH and Roland N. NDIP (2012) Antioxidant and antimicrobial properties of acetone and aqueous extracts of mature stem bark of Sclerocarya birrea Evidenced Based Complementary and Alternative Medicine. 2012: 834156
25. Mirriam E. Nyenje , Roland N. Ndip (2012). Bioactivity of the acetone extract of the stem bark of Combretum molle on selected bacterial pathogens: Preliminary phytochemical screening. Journal of Medicinal Plants Research. 6 : 1476 – 1481.
26. Wilfred Mbeng OTANG, Donald Scott GRIERSON, Roland Ndip NDIP (2012)
Antifungal activity of Arctotis arctotoides (L.f.) O. Hoffm. and Gasteria bicolor Haw. against opportunistic fungi associated with HIV/AIDS. Pharmacognosy magazine. 8 (30): 135 -140
27. Wilfred M Otang, Donald S Grierson and Roland N Ndip (2012). Phytochemical studies and antioxidant activity of two South African medicinal plants traditionally used for the management of opportunistic fungal infections in HIV/AIDS patients. BMC Complementary and Alternative Medicine. 12:43
28. Tracy M. Masebe, Julius M. Nwobegahay, Debra Meyer, Roland N. Ndip, Benson Iweriebor, Pascal O. Bessong (2012). Prevalence of MDR1 C3435T and CYP2B6 G516T polymorphisms among HIV-1 infected South African patients. Disease Markers. 32 (1): 43 – 50.
29. Otang WM, Grierson D, Ndip RN (2012). Ethnobotanical survey of medicinal plants used in the management of opportunistic fungal infections in HIV/AIDS patients in the Amathole District of the Eastern Cape Province, South Africa. Journal of Medicinal Plants Research. 6 (11): 2071 – 2080
30. Christy E. Manyi –Loh , Anna M. Clarke, Roland N. Ndip. (2011). Identification of volatile compounds in solvent extracts of honeys produced in South Africa. African Journal of Agricultural Research. 6 (18) : 4327 – 4334
31. Benjamin I Okeleye, Pascal O. Bessong, Roland N. Ndip (2011). Preliminary phytochemical screening and in vitro anti- Helicobacter pylori activity of extracts of the stem bark of Bridelia micrantha. ( Hochst., Baill., Euphorbiaceae). Molecules. 16: 6193 – 6205
32. Christy E. Manyi –Loh , Roland N. Ndip and Anna M. Clarke, (2011). Volatile compounds in honey: A review on their involovement in aroma, botanical origin determination and potential biomedical activities. International Journal of Molecular Sciences. 12: 9514 – 9532
33. Wilfred M. OTANG, Donald S. GRIERSON and Roland N. NDIP (2011). The effect of the acetone extract of Arctotis arctotoides (Asteraceae) on the gross morphology and ultrastructure of some opportunistic fungi associated with HIV/AIDS. International Journal of Molecular Sciences. 12: 9226 – 9235
34. Nicoline F. Tanih, Lucy M. Ndip, Roland N Ndip (2011). DNA sequence analysis of South African Helicobacter pylori vacuolating cytotoxin gene (vacA). International Journal of Molecular Sciences. 12: 7459 – 7468
35. Otang WM, Grierson D, Ndip RN (2011). Prevalence, perceived benefits and effectiveness of herbal medicine in the management of symptoms of opportunistic fungal infections in HIV/AIDS patients in the Eastern Cape, South Africa. African Journal of Biotechnology. 10 (83) : 19458 – 19463
36. Nkomo LP, Green E, Ndip RN (2011). Preliminary phytochemical screening and in vitro anti- Helicobacter pylori activity of extracts of the leaves of Lippia javanica. African Journal of Pharmacy and Pharmacology. 5 (20): 2184 – 2192.
37. Nethathe BB, Ndip RN (2011). Bioactivity of Hydonora africana on selected bacterial pathogens: Preliminary phytochemical screening. African Journal of Microbiology Research. 5 (18): 2820 – 2826
38. Nyenje M, Ndip RN (2011). In-vitro antimicrobial activity of the crude acetone extract of the stem bark of combretum molle against selected bacterial pathogens of medical importance. Journal of Medicinal Plants Research. 5(21): 5315 -5320
39. Adefuye AA, Samie A, Ndip RN (2011). In-vitro evaluation of the antimicrobial activity of extracts of Bridelia micrantha on selected bacterial pathogens. Journal of Medicinal Plants Research. 5(20): 5116 – 5122
40. Seraphine NF Esemu, Lucy M. Ndip, Roland N. Ndip (2011). Ehrlichia species as probable emerging pathogens in sub-Saharan Africa: Environmental exacerbation. Reviews on Environmental Health. 26 (4): 269 – 279.
41. Njume C, Afolayan A J, Ndip R N (2011). Aqueous and organic solvent- extracts of selected medicinal plants possess antimicrobial activity against drug resistant strains of Helicobacter pylori: inhibitory and bactericidal potential. International Journal of Molecular Sciences. 12: 5652 – 5665.
42. Ezekiel Green, Lawrence C. Obi, Samie Amidou, Pascal O. Bessong, Roland N. Ndip (2011). Characterization of n-Hexane sub-fraction of Bridelia micrantha (Berth) and its antimycobacterium activity. BMC Alternative and Complementary Medicine. 11:28
43. Njume C, Afolayan A.J, Samie A, Ndip R.N (2011). In-vitro anti-Helicobacter pylori activity of acetone, ethanol and methanol extracts of the stem bark of Combretum molle R.Br. ex G. Don (Combretaceae). Journal of Medicinal Plants Research 5(14): 3210 3216
44. Collise Njume, Afolayan Anthony Jide, Samie Amidou, Ndip Roland Ndip (2011). Inhibitory and bactericidal potential of crude acetone extracts of Combretum molle (Combretaceae) on clinical isolates of Helicobacter pylori. Journal of Health, Population and Nutrition. 29 (5): 438 – 445
45. Njume C, Afolayan AJ, Ndip RN (2011). Diversity of plants used in the treatment of Helicobacter pylori associated morbidities in the Nkonkobe municipality of the Eastern Cape province of South Africa. Journal of Medicinal Plants Research 5(14): 3146 -3151.
46. Njume C , Afolayan AJ , Green E Ndip RN (2011). Volatile compounds in the stem bark of Sclerocarya birrea (Anacardiaceae) possess potent antimicrobial activity against drug-resistant Helicobacter pylori. International Journal of Antimicrobial Agents . 38 (4): 319 – 24
47. Njume C, Afolayan AJ, Ndip RN (2011). Preliminary phytochemical screening and in-vitro anti- Helicobacter pylori activity of acetone and aqueous extracts of the stem bark of Sclerocarya birrea (Anacardiaceae). Archives of Medical Research . 42 (3): 252 – 257
48. Nicoline F. Tanih, Lucy M. Ndip, Roland N. Ndip (2011). Characterization of metronidazole (rdxA and frxA) and clarithromycin resistance (23SrRNA) genes in South African Helicobacter pylori strains. Annals of Tropical Medicine and Parasitology. 105(3): 251-259
49. Christy E. Manyi –Loh, Anna M. Clarke, Roland N. Ndip (2011). An overview of honey: therapeutic properties and contribution in nutrition and human health. African Journal of Microbiology Research. 5 (8): 844 – 852
50. Njume C, Afolayan AJ, Clarke AM, Ndip RN (2011). Crude ethanolic extracts of Garcinia kola seeds Heckel (Guttiferae) prolong the lag phase of Helicobacter pylori: inhibitory and bactericidal potential. Journal of Medicinal Food. 14 (7): 822 – 827
51. Omoruyi B, Matongo F, Mkwetshana NF, Green E, Clark AM, Ndip RN (2011).Risk factors associated with prevalence of Cryptosporidium infection in the Alice rural settlements of the Eastern Cape Province of South Africa: a pilot study. Reviews on Environmental Health. 26 (2): 127 – 133
52. Ndip LM, Biswas HH, Nfonsam LE, Lebreton M, Ndip RN, Bissong MA, Mpoudi-Ngole E, Djoko C, Tamoufe U, Prosser AT, Burke DS, Wolfe ND. (2011). Risk Factors for African Tick-Bite Fever in Rural Central Africa. American Journal of Tropical Medicine and Hygiene. 84(4):608-613.
53. Christy E. Manyi-Loh, Anna M. Clarke, Munzhelele T, E. Green, NF Mkwetshana, RN Ndip (2010). Selected South African honeys and their extracts possess In vitro anti- Helicobacter pylori activity. Archives of Medical Research. 41: 324 – 331
54. Ezekiel Green, Samie Amidou, Larry C. Obi, Pascal O. Bessong, Roland N. Ndip (2010). Inhibitory properties of selected South African medicinal plants against Mycobacterium tuberculosis. Journal of Ethnopharmacology. 130 (1): 151 -157
55. Nicoline F. Tanih, Martin McMillan , Nathan Naidoo, Lucy M. Ndip Lawrence T. Weaver, Roland N. Ndip (2010). Prevalence of Helicobacter pylori vacA, cagA and iceA genotypes in South African patients with upper gastrointestinal diseases. Acta Tropica. 116 (1): 68 – 73
56. Tanih NF, Okeleye BI, Ndip LM, Clarke AM, Naidoo N, Mkwetshana N, Green E, Ndip RN (2010). Helicobacter pylori prevalence in dyspeptic patients in the Eastern Cape Province of South Africa: race and disease status. South African Medical Journal. 100(11): 734 – 737
57. Okeleye BI, Samie A. Bessong PO, Mkwetshana NF, Green E, Clarke AM, Ndip R.N (2010). Crude Ethyl Acetate Extract of the Stem Bark of Peltophorum africanum (Sond, Fabaceae) possesses in vitro inhibitory and bactericidal activity against clinical isolates of Helicobacter pylori. Journal of Medicinal Plants Research. 4(14): 1432 – 1440
58. Tanih NF, Ndip LM, Clarke AM, Ndip RN (2010). An overview of Pathogenesis and Epidemiology of Helicobacter pylori infection. African Journal of Microbiology Research. 4(6): 426-436
59. Tanih NF, Okeleye BI, Clarke AM , Naidoo N , Mkwetshana N, Green E, Ndip LM, Ndip RN (2010). Marked susceptibility of South African Helicobacter pylori strains to ciprofloxacin and amoxicillin: clinical implications. South African Medical Journal . 100: 49-52
60. Green E., C.L. Obi, M. Nchabeleng, B.E. de Villiers, P.P. Sein, T. Letsoalo,
A.A. Hoosen, P.O. Bessong, and Roland N. Ndip (2010). Drug susceptibility pattern of Mycobacterium tuberculosis in Mpumalanga Province, South Africa: possible guiding design of retreatment regimen. Journal of Health, Population and Nutrition . 28(1): 7-13
61. Novosti Buta, Nicoline F. Tanih, Roland N. Ndip (2010). Increasing trends of metronidazole resistance in the treatment of Helicobacter pylori infection: A global challenge. African Journal of Biotechnology 9(8): 1115-1121.
62. Christy E. Manyi –Loh, Anna M. Clarke, Noxolo T. Mkwetshana, Roland N. Ndip (2010). Treatment of Helicobacter pylori Infections: Mitigating factors and prospective natural remedies. African Journal of Biotechnology 9(14): 2032-2042.
Personal Summary
Professor Roland N. NDIP obtained his PhD in 1994 from the Edo State University, Ekpoma, Nigeria. He has worked as a professional Microbiologist for over 20 years, successively at Edo State University, Nigeria; University of Fort Hare, South Africa and the University of Buea, Cameroon rising to the rank of Professor of Microbiology. His research has concentrated in the areas of Microbiology, Molecular biology, Antimicrobial Chemotherapy and Alternative and Complementary Medicine. The central theme of his research lies in the diagnosis, epidemiology and control of bacterial pathogens.
He has supervised several doctoral and master’s theses, and currently has over 100 articles published in international peer reviewed journals of repute in addition to 3 book chapters. He has attended and presented papers at several local, regional and international conferences.
He is member to several professional and academic societies and serves as editorial board member of several journals and external examiner to both national and international universities. In addition to his teaching and research engagements, he also currently serves as Registrar of the University.
